Ionic Liquid as an Efficient Medium for the Synthesis of Quinoline Derivatives via α-Chymotrypsin-Catalyzed Friedländer Condensation

An efficient, convenient, and eco-friendly biocatalytic approach was developed for the synthesis of quinoline derivatives via the α-chymotrypsin-catalyzed Friedländer reaction. Interestingly, α-chymotrypsin exhibited higher catalytic activity in an ionic liquid (IL) aqueous solution as compared to t...

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Autors principals:	Zhang-Gao Le, Meng Liang, Zhong-Sheng Chen, Sui-Hong Zhang, Zong-Bo Xie
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2017-05-01
Col·lecció:	Molecules
Matèries:	Friedländer reaction quinolines α-chymotrypsin ionic liquid biocatalysis promiscuity
Accés en línia:	http://www.mdpi.com/1420-3049/22/5/762
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