Faecalibacterium prausnitzii prevents age-related heart failure by suppressing ferroptosis in cardiomyocytes through butyrate-mediated LCN2 regulation

Aging is a primary driver of the escalating prevalence of heart failure (HF). Age-associated gut microbiota dysbiosis has been implicated in various age-related diseases, yet its role in age-related HF remains largely unexplored. In this study, we sought to explore the potential link between age-rel...

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Hauptverfasser:	Yun Zhang, Ying Wei, Xuejie Han, Ling Shi, Hui Yu, Xuanrui Ji, Yunlong Gao, Qianhui Gao, Linwei Zhang, Yu Duan, Wenpeng Li, Yue Yuan, Jing Shi, Liang Cheng, Yue Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2025-12-01
Schriftenreihe:	Gut Microbes
Schlagworte:	Heart failure aging F. prausnitzii butyrate ferroptosis
Online-Zugang:	https://www.tandfonline.com/doi/10.1080/19490976.2025.2505119
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