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Cetrorelix promotes cell apoptosis via the PI3K–AKT–FOXO1 pathway in epithelial ovarian cancer

IntroductionEpithelial ovarian cancer (EOC) has a dismal prognosis, and recent therapeutic advancements have been limited. The aim of our study was to clarify the role and mechanism of cetrorelix in EOC apoptosis and to evaluate the clinical relevance of GnRHR, AKT, and FOXO1 in EOC patients.Methods...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ning Zhang, Yu Liu, Xiaodan Zhang, Meng Xie, Ying Zhang, Keqin Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2025-12-01
Cyfres:Frontiers in Oncology
Pynciau:
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fonc.2025.1631576/full
Tagiau: Ychwanegu Tag
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