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Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice

Summary: Individuals with fragile X syndrome (FXS) are frequently diagnosed with autism spectrum disorder (ASD), including increased risk for restricted and repetitive behaviors (RRBs). Consistent with observations in humans, FXS model mice display distinct RRBs and hyperactivity that are consistent...

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Ngā kaituhi matua: Francesco Longo, Sameer Aryal, Paul G. Anastasiades, Marta Maltese, Corey Baimel, Federica Albanese, Joanna Tabor, Jeffrey D. Zhu, Mauricio M. Oliveira, Denise Gastaldo, Claudia Bagni, Emanuela Santini, Nicolas X. Tritsch, Adam G. Carter, Eric Klann
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2023-08-01
Rangatū:Cell Reports
Ngā marau:
CP: Neuroscience
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124723009129
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