Ovalbumin-specific CD4+ and CD8+ T cells contribute to different susceptibility for Theiler’s murine encephalomyelitis virus persistence

Theiler’s murine encephalomyelitis virus (TMEV) is the causative agent of TMEV-induced demyelinating disease (TMEV-IDD); a well-established animal model for the chronic progressive form of human multiple sclerosis (MS). In susceptible mice with an inadequate immune response, TMEV-IDD is triggered by...

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Detalhes bibliográficos

Principais autores:	Rouven Wannemacher, Anna Reiß, Karl Rohn, Fred Lühder, Alexander Flügel, Wolfgang Baumgärtner, Kirsten Hülskötter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-05-01
Colecção:	Frontiers in Immunology
Assuntos:	central nervous system OT mice Theiler’s murine encephalomyelitis virus (TMEV) OVA-specific CD8+ T cells OVA-specific CD4+ T cells microgliosis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1194842/full
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