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Prevalence of Pathogenic Germline DICER1 Variants in Young Individuals Thyroidectomised Due to Goitre – A National Danish Cohort

IntroductionDICER1 syndrome encompasses a variety of benign and malignant manifestations including multinodular goitre, which is the most common manifestation among individuals carrying pathogenic DICER1 variants. This is the first study estimating the prevalence of pathogenic DICER1 variants in you...

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Principais autores: Mays Altaraihi, Thomas van Overeem Hansen, Eric Santoni-Rugiu, Maria Rossing, Åse Krogh Rasmussen, Anne-Marie Gerdes, Karin Wadt
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Endocrinology
Assuntos:
goitre
thyroidectomy
hereditary cancer
DICER1 syndrome
DICER1 mutation
goiter
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fendo.2021.727970/full
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