Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure

Levonorgestrel (LNG) is a progestin used in many contraceptive formulations, including subcutaneous implants. There is an unmet need for developing long-acting formulations for LNG. To develop long-acting formulations, release functions need to be investigated for LNG implant. Therefore, a release m...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Soyoung Kim, Brian Cicali, Michelle Pressly, Lais Da Silva, Thomas Wendl, Valvanera Vozmediano, Stephan Schmidt, Rodrigo Cristofoletti
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-05-01
coleção:	Pharmaceutics
Assuntos:	hormonal contraceptives subcutaneous implants PBPK modeling
Acesso em linha:	https://www.mdpi.com/1999-4923/15/5/1393
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!