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Leishmanicidal and Immunomodulatory Activities of the Palladacycle Complex DPPE 1.1, a Potential Candidate for Treatment of Cutaneous Leishmaniasis

The present study focused on the activity of the palladacycle complex DPPE 1.1 on Leishmania (Leishmania) amazonensis. Promastigotes of L. (L.) amazonensis were destroyed in vitro by nanomolar concentrations of DPPE 1.1, whereas intracellular amastigotes were killed at drug concentrations fivefold l...

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Principais autores: Isabela B. dos Santos, Danielle A. M. da Silva, Fabiana A. C. R. Paz, Daniel M. Garcia, Adriana K. Carmona, Daniela Teixeira, Ieda M. Longo-Maugéri, Simone Katz, Clara L. Barbiéri
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Assuntos:
cutaneous leishmaniasis
leishmaniasis treatment
Leishmania (Leishmania) amazonensis
palladacycle complex
immunomodulation
Acceso en liña:https://www.frontiersin.org/article/10.3389/fmicb.2018.01427/full
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