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Imaging the directed transport of single engineered RNA transcripts in real-time using ratiometric bimolecular beacons.

The relationship between RNA expression and cell function can often be difficult to decipher due to the presence of both temporal and sub-cellular processing of RNA. These intricacies of RNA regulation can often be overlooked when only acquiring global measurements of RNA expression. This has led to...

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Principais autores: Xuemei Zhang, Allison L Zajac, Lingyan Huang, Mark A Behlke, Andrew Tsourkas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3893274?pdf=render
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