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The Flp type IV pilus operon of Mycobacterium tuberculosis is expressed upon interaction with macrophages and alveolar epithelial cells

The genome of Mycobacterium tuberculosis (Mtb) harbors the genetic machinery for assembly of the Fimbrial low-molecular-weight protein (Flp) type IV pilus. Presumably, the Flp pilus is essential for pathogenesis. However, it remains unclear whether the pili genes are transcribed in culture or during...

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Principais autores: Christopher J. Alteri, Nora Rios-Sarabia, Miguel A. De la Cruz, Jorge A. González-y-Merchand, Jorge Soria-Bustos, Carmen Maldonado-Bernal, María L. Cedillo, Jorge A. Yáñez-Santos, Ygnacio Martínez-Laguna, Javier Torres, Richard L. Friedman, Jorge A. Girón, Miguel A. Ares
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular and Infection Microbiology
Assuntos:
tuberculosis
mycobacteria
pili
adherence
virulence
biofilms
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fcimb.2022.916247/full
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