Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications

The nicotinic acetylcholine receptor (nAChR) is a major target of autoantibodies in myasthenia gravis (MG), an autoimmune disease that causes neuromuscular transmission dysfunction. Despite decades of research, the molecular mechanisms underlying MG have not been fully elucidated. Here, we present t...

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Prif Awduron:	Kaori Noridomi, Go Watanabe, Melissa N Hansen, Gye Won Han, Lin Chen
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	eLife Sciences Publications Ltd 2017-04-01
Cyfres:	eLife
Pynciau:	myasthenia gravis nicotinic acetylcholine receptors crystallography autoantibodies Pichia pastoris
Mynediad Ar-lein:	https://elifesciences.org/articles/23043
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