Regulation of Paneth cell-specific genes in COVID-19 patients and SARS-CoV-2-infected mice by quantification of mRNA from exfoliated cells in stool samples

Abstract The Paneth cell, a secretory cell of the small intestine, expresses numerous host defense proteins, and is hypothesized to play an important role in host defense against infection. However, studying gene expression in this cell requires invasive procedures. To test the hypothesis that we co...

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Egile Nagusiak:	Gill Diamond, Erika L. Figgins, Denny Gao, Tanya O. Robinson, Kenneth Wilson, Jon D. Gabbard, Charles D. Anderson, Lalit Batra, Chithra Sreenivasan, Jian Zheng, Uyen Do, Braden Mulcahy, Lisa K. Ryan, Nathaniel McLaughlin, Anna H. Owings, Neha Dhaliwal, Haley B. Williams, T. Grant Wichman, Michelle Galeas-Pena, Sarah C. Glover
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2024-12-01
Saila:	Scientific Reports
Gaiak:	Small intestine Biomarker SARS-CoV-2 Defensin
Sarrera elektronikoa:	https://doi.org/10.1038/s41598-024-82098-z
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