Impact of excessive hypercholesterolemia in pregnancy on the placentas of the male and female offspring

Abstract Excessive hypercholesterolemia (eHC) in pregnancy reduces placental efficiency in both fetal sexes, but the mechanisms are not known. In this study, Sprague Dawley rats received a control or high cholesterol diet (to model eHC) during pregnancy, after which various markers of placental func...

Descripción completa

Detalles Bibliográficos

Autores principales:	Amanda A. de Oliveira, Angie Stokes, Anita Quon, Murilo E. Graton, Floor Spaans, Christy-Lynn M. Cooke, Sandra T. Davidge
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-07-01
Colección:	Scientific Reports
Materias:	Hypercholesterolemia in pregnancy Placenta Cholesterol receptors and transporters Unfolded protein response NLRP3 inflammasome
Acceso en línea:	https://doi.org/10.1038/s41598-025-11416-w
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!