Tumor-Derived Extracellular Vesicles Induce Abnormal Angiogenesis via TRPV4 Downregulation and Subsequent Activation of YAP and VEGFR2

Tumor angiogenesis is initiated and maintained by the tumor microenvironment through secretion of autocrine and paracrine factors, including extracellular vesicles (EVs). Although tumor-derived EVs (t-EVs) have been implicated in tumor angiogenesis, growth and metastasis, most studies on t-EVs are f...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Brianna Guarino, Venkatesh Katari, Ravi Adapala, Neha Bhavnani, Julie Dougherty, Mahmood Khan, Sailaja Paruchuri, Charles Thodeti
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2021-12-01
Saila:	Frontiers in Bioengineering and Biotechnology
Gaiak:	endothelial cells extracellular vesicles transient receptor potential vanilloid 4 tumor angiogenesis vascular endothelial growth factor receptor 2
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.790489/full
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!