Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains.

The human immunity-related GTPase M (IRGM) has been shown to be critically involved in regulating autophagy as a means of disposing cytosolic cellular structures and of reducing the growth of intracellular pathogens in vitro. This includes Mycobacterium tuberculosis, which is in agreement with findi...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Christopher D Intemann, Thorsten Thye, Stefan Niemann, Edmund N L Browne, Margaret Amanua Chinbuah, Anthony Enimil, John Gyapong, Ivy Osei, Ellis Owusu-Dabo, Susanne Helm, Sabine Rüsch-Gerdes, Rolf D Horstmann, Christian G Meyer
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2009-09-01
Цуврал:	PLoS Pathogens
Онлайн хандалт:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19750224/pdf/?tool=EBI
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!