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Dispersal of Group A streptococcal biofilms by the cysteine protease SpeB leads to increased disease severity in a murine model.

Group A Streptococcus (GAS) is a Gram-positive human pathogen best known for causing pharyngeal and mild skin infections. However, in the 1980's there was an increase in severe GAS infections including cellulitis and deeper tissue infections like necrotizing fasciitis. Particularly striking about th...

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Hlavní autoři: Kristie L Connolly, Amity L Roberts, Robert C Holder, Sean D Reid
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2011-04-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3081844?pdf=render
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