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Including non-concurrent control patients in the analysis of platform trials: is it worth it?

Abstract Background Platform trials allow adding new experimental treatments to an on-going trial. This feature is attractive to practitioners due to improved efficiency. Nevertheless, the operating characteristics of a trial that adds arms have not been well-studied. One controversy is whether just...

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Bibliografiske detaljer
Principais autores: Kim May Lee, James Wason
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-06-01
Serier:BMC Medical Research Methodology
Fag:
Online adgang:http://link.springer.com/article/10.1186/s12874-020-01043-6
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