Transposable Elements in Pluripotent Stem Cells and Human Disease

Transposable elements (TEs) are mobile genetic elements that can randomly integrate into other genomic sites. They have successfully replicated and now occupy around 40% of the total DNA sequence in humans. TEs in the genome have a complex relationship with the host cell, being both potentially dele...

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Hlavní autoři:	Gang Ma, Isaac A. Babarinde, Xuemeng Zhou, Andrew P. Hutchins
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-06-01
Edice:	Frontiers in Genetics
Témata:	transposable element (TE) endogenous retrovirus (ERV) long terminal repeat (LTR) pluripotent stem cell (PSC) non-coding RNA (ncRNAs)
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fgene.2022.902541/full
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