siRNA Specificity: RNAi Mechanisms and Strategies to Reduce Off-Target Effects
Short interfering RNAs (siRNAs) are processed from long double-stranded RNA (dsRNA), and a guide strand is selected and incorporated into the RNA-induced silencing complex (RISC). Within RISC, a member of the Argonaute protein family directly binds the guide strand and the siRNA guides RISC to fully...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2021-01-01
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| Reeks: | Frontiers in Plant Science |
| Onderwerpen: | |
| Online toegang: | https://www.frontiersin.org/articles/10.3389/fpls.2020.526455/full |
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