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Deep learning‐based identification of sinoatrial node‐like pacemaker cells from SHOX2/HCN4 double‐positive cells differentiated from human iPS cells

Abstract Background Cardiomyocytes derived from human iPS cells (hiPSCs) include cells showing SAN‐ and non‐SAN‐type spontaneous APs. Objectives To examine whether the deep learning technology could identify hiPSC‐derived SAN‐like cells showing SAN‐type‐APs by their shape. Methods We acquired phase‐...

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Principais autores: Takayuki Wakimizu, Junpei Naito, Manabu Ishida, Yasutaka Kurata, Motokazu Tsuneto, Yasuaki Shirayoshi, Ichiro Hisatome
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2023-08-01
coleção:Journal of Arrhythmia
Assuntos:
automaticity
CNN model
deep learning
human iPS cells
SAN‐like cells
Acesso em linha:https://doi.org/10.1002/joa3.12883
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