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Functional Characterization of Ubiquitin-Like Core Autophagy Protein ATG12 in Dictyostelium discoideum

Autophagy is a highly conserved intracellular degradative pathway that is crucial for cellular homeostasis. During autophagy, the core autophagy protein ATG12 plays, together with ATG5 and ATG16, an essential role in the expansion of the autophagosomal membrane. In this study we analyzed gene replac...

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Principais autores: Sarah Fischer, Ramesh Rijal, Peter Frommolt, Prerana Wagle, Roman Konertz, Jan Faix, Susanne Meßling, Ludwig Eichinger
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-01-01
Serier:Cells
Fag:
ATG12
ATG16
autophagy
Dictyostelium
ubiquitin-like protein
post-translational modifier
phagocytosis
pinocytosis
proteasome
ubiquitin proteasome system (UPS)
Online adgang:http://www.mdpi.com/2073-4409/8/1/72
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