Monosodium urate crystals exposure is associated with limited transcriptional changes in primary human PBMCs

Monosodium urate (MSU) crystals are the primary cause of gout, however the knowledge on MSU crystals exposure and inflammatory changes found in immune cells is diverse, with reports ranging from very limited inflammatory effects to substantial reprogramming of the cells induced by MSU crystals alone...

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Detalles Bibliográficos

Principais autores:	Nica Valentin, Badii Medeea, Gaal Orsolya, Cabău Georgiana, Cleophas Maartje, Naidu Akshayata, Hotea Ioana, Jansen Tim L., Pamfil Cristina, Rednic Simona, Popp Radu A., Li Yang, Crișan Tania O., Joosten Leo A.B.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Sciendo 2025-09-01
Series:	Romanian Journal of Internal Medicine
Assuntos:	gout monosodium urate palmitate peripheral blood human mononuclear cells transcriptomics cytokine
Acceso en liña:	https://doi.org/10.2478/rjim-2025-0019
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