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Extent of polymorphism and selection pressure on the Trypanosoma cruzi vaccine candidate antigen Tc24

Abstract Introduction Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major public health problem in the Americas, and existing drugs have severe limitations. In this context, a vaccine would be an attractive alternative for disease control. One of the difficulties in develo...

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Principais autores: Audrey Arnal, Liliana Villanueva‐Lizama, Christian Teh‐Poot, Claudia Herrera, Eric Dumonteil
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2020-12-01
Serija:Evolutionary Applications
Teme:
Online dostop:https://doi.org/10.1111/eva.13068
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