Non-invasive assessment of activated renal macrophages by imaging of colony-stimulating factor 1 receptor in mouse model with ischemic acute kidney injury

Abstract Background Emerging evidence suggests that renal inflammation, characterized by the activation of renal macrophages, plays a critical role in the pathogenesis of kidney diseases, including acute kidney injury (AKI). However, reliable research methods for visualizing renal macrophages remain...

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Κύριοι συγγραφείς:	Sijun Chen, Xinran Zhao, Yanshan Li, Nailian Zhang, Xiyan Rui, Xuejing Guan, Fangfei Hu, Chie Seki, Lin Xie, Ming-Rong Zhang, Mei Tian, Bin Ji, Rong Zhou
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2025-11-01
Σειρά:	Journal of Inflammation
Θέματα:	Ischemia-reperfusion-induced acute kidney injury (I/R-AKI) Inflammation Macrophages Colony-stimulating factor 1 receptor (CSF1R) Positron emission tomography (PET) Autoradiography
Διαθέσιμο Online:	https://doi.org/10.1186/s12950-025-00482-6
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