Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion

Antiviral effectors such as natural killer (NK) cells have impaired functions in chronic hepatitis B (CHB) patients. The molecular mechanism responsible for this dysfunction remains poorly characterised. We show that decreased cytokine production capacity of peripheral NK cells from CHB patients was...

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Detalhes bibliográficos

Principais autores:	Marie Marotel, Marine Villard, Annabelle Drouillard, Issam Tout, Laurie Besson, Omran Allatif, Marine Pujol, Yamila Rocca, Michelle Ainouze, Guillaume Roblot, Sébastien Viel, Melissa Gomez, Veronique Loustaud, Sophie Alain, David Durantel, Thierry Walzer, Uzma Hasan, Antoine Marçais
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2021-01-01
coleção:	eLife
Assuntos:	natural killer dysfunction calcium pathway mTOR
Acesso em linha:	https://elifesciences.org/articles/60095
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