Deciphering genetic causality between plasma BDNF and 91 circulating inflammatory proteins through bidirectional mendelian randomization

Abstract Prior studies reported an association between the levels of brain-derived neurotrophic factor (BDNF) circulating in the bloodstream and those of different inflammatory factors. However, their causal relationship remains unclear. Here, we performed a Mendelian randomization (MR) study to inv...

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Váldodahkkit:	Yesheng Sun, Xizi Shi, Melanie Ohm, Martin Korte, Marta Zagrebelsky
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Nature Portfolio 2025-03-01
Ráidu:	Scientific Reports
Fáttát:	BDNF Neurotrophin family Inflammatory cytokines Aging Mendelian randomization
Liŋkkat:	https://doi.org/10.1038/s41598-025-95546-1
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