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Association of TP53 rs1042522 G > C, MDM2 rs2279744 T > G, and miR-34b/c rs4938723 T > C polymorphisms with aneuploidy pregnancy susceptibility

Abstract Background Aneuploidy pregnancy is a severe major birth defect and causes about 50% spontaneous miscarriages with unknown etiology. To date, only a few epidemiological studies with small sample sizes have investigated the risk factors for aneuploidy pregnancy. TP53, MDM2, and miR-34b/c gene...

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主要な著者: Ying Chan, Weiming Xu, Yan Feng, Yan Zhang, Suyun Li, Zibiao Geng, Zhijiao Liu, Qingfen Zhao, Jinman Zhang, Baosheng Zhu
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2023-08-01
シリーズ:BMC Pregnancy and Childbirth
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オンライン・アクセス:https://doi.org/10.1186/s12884-023-05945-3
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