Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

Abstract Background Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. However, it is not known if or when corticosteroids can...

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Autors principals:	Amber J. Giles, Marsha-Kay N. D. Hutchinson, Heather M. Sonnemann, Jinkyu Jung, Peter E. Fecci, Nivedita M. Ratnam, Wei Zhang, Hua Song, Rolanda Bailey, Dionne Davis, Caitlin M. Reid, Deric M. Park, Mark R. Gilbert
Format:	Artigo
Idioma:	Inglês
Publicat:	BMJ Publishing Group 2018-06-01
Col·lecció:	Journal for ImmunoTherapy of Cancer
Matèries:	Corticosteroids Immunotherapy Glioma Checkpoint blockade Dexamethasone
Accés en línia:	http://link.springer.com/article/10.1186/s40425-018-0371-5
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