Relationship of an hRAD54 gene polymorphism (2290 C/T) in an Ecuadorian population with chronic myelogenous leukemia

The hRAD54 gene is a key member of the RAD52 epistasis group involved in repair of double-strand breaks (DSB) by homologous recombination (HR). Thus, alterations of the normal function of these genes could generate genetic instability, shifting the normal process of the cell cycle, leading the cells...

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Hlavní autoři:	César Paz-y-Miño, Andrés López-Cortés, María José Muñoz, Bernardo Castro, Alejandro Cabrera, María Eugenia Sánchez
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Sociedade Brasileira de Genética 2010-01-01
Edice:	Genetics and Molecular Biology
Témata:	cancer leukemia CML ALL hRAD54 2290 C/T polymorphism
On-line přístup:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000400009
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