In vitro activity of antibiotic monotherapy and combination therapy with bacteriophages against Staphylococcus aureus LVAD-driveline infections

ABSTRACT Left-ventricular assist devices (LVADs) are increasingly used as a bridge to heart transplantation and destination therapy. These devices, especially the driveline, are susceptible to difficult-to-treat infections, associated with high morbidity and mortality rates. Staphylococcus aureus (S...

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Huvudupphov:	Michèle M. Molendijk, Nelianne J. Verkaik, Corné P. de Vogel, Nicole Lemmens-den Toom, Gwenan M. Knight, Kadir Caliskan, Lonneke G. M. Bode, Annelies Verbon, Marion P. G. Koopmans, Miranda de Graaf, Willem J. B. van Wamel
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology 2025-11-01
Serie:	Journal of Clinical Microbiology
Ämnen:	LVAD driveline infection biofilm Staphylococcus aureus bacteriophages isothermal microcalorimetry
Länkar:	https://journals.asm.org/doi/10.1128/jcm.00272-25
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