Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells

Abstract The pancreas is comprised of exocrine and endocrine compartments releasing digestive enzymes into the duodenum and regulating blood glucose levels by insulin and glucagon release. Tissue homeostasis is depending on transcription factor networks, involving Ptf1α, Ngn3, Nkx6.1, and Sox9, whic...

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Detalhes bibliográficos

Principais autores:	María Lasierra Losada, Melissa Pauler, Niels Vandamme, Steven Goossens, Geert Berx, Moritz Leppkes, Harald Schuhwerk, Simone Brabletz, Thomas Brabletz, Marc P. Stemmler
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2021-06-01
coleção:	Cell Death Discovery
Acesso em linha:	https://doi.org/10.1038/s41420-021-00522-z
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