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Plagiochiline A Inhibits Cytokinetic Abscission and Induces Cell Death

We previously reported on the isolation and biological activities of plagiochiline A (1), a 2,3-secoaromadendrane-type sesquiterpenoid from the Peruvian medicinal plant, Plagiochila disticha. This compound was found to have antiproliferative effects on a variety of solid tumor cell lines, as well as...

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Main Authors: Nicole S. Stivers, Ashraful Islam, Elsa M. Reyes-Reyes, Lavona K. Casson, José C. Aponte, Abraham J. Vaisberg, Gerald B. Hammond, Paula J. Bates
Format: Artigo
Language:Inglês
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
plagiochiline A
Plagiochila disticha
cytokinesis
abscission
Online Access:http://www.mdpi.com/1420-3049/23/6/1418
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