Mechanism of μ-opioid receptor inhibition by orphan GPR88

From the approximately 800 members of the G protein-coupled receptor (GPCR) family, more than 100 remain orphans (oGPCRs). There is evidence indicating that some oGPCRs may carry out a physiological role independently from endogenous ligands; this includes forming heteromers with other GPCRs and alt...

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Bibliografski detalji

Glavni autori:	Claudia Llinas del Torrent, Iu Raïch, Berta Carrasco-Martinez, Jaume Lillo, Maria Gallo, David Andreu, Leonardo Pardo, Gemma Navarro
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-02-01
Serija:	Pharmacological Research
Teme:	OGPCRs GPR88 µOR Heteromers Striatal neurons In Situ Proximity Ligation Assay (PLA)
Online pristup:	http://www.sciencedirect.com/science/article/pii/S1043661825005092
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