Umbilical cord blood CD34+ progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rgnull mice

Adoptive transfer of allogeneic natural killer (NK) cells is an attractive therapy approach against ovarian carcinoma. Here, we evaluated the potency of highly active NK cells derived from human CD34+ haematopoietic stem and progenitor cells (HSPC) to infiltrate and mediate killing of human ovarian...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Janneke S. Hoogstad-van Evert, Jeannette Cany, Dirk van den Brand, Manon Oudenampsen, Roland Brock, Ruurd Torensma, Ruud L. Bekkers, Joop H. Jansen, Leon F. Massuger, Harry Dolstra
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis Group 2017-08-01
Sarja:	OncoImmunology
Aiheet:	adoptive immunotherapy mouse ovarian cancer xenograft nk cells ovarian cancer tumor spheroid infiltration
Linkit:	http://dx.doi.org/10.1080/2162402X.2017.1320630
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