Bioactivity of Thyroid Hormone Analogs at Cancer Cells
In the context of genomic thyroid hormone actions in normal (noncancer) cells that involve primary interactions with nuclear thyroid hormone receptors (TRs), L-thyroxine (T4), and 3,3′,5′-triiodo-L-thyronine (reverse T3, rT3) have little bioactivity. In terms of TRs, T4 is a prohormone from which th...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018-12-01
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| coleção: | Frontiers in Endocrinology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/article/10.3389/fendo.2018.00739/full |
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