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Serial assessment of serum HMGB1 and ΔSOFA for predicting 28-day mortality in sepsis patients: a prospective cohort study in the emergency department

Abstract Background Prognostic assessment in sepsis involves evaluating the dynamic progression of organ dysfunction and the inflammatory response. This study compared the predictive value of serially measured serum HMGB1, a key late mediator of sepsis, with the ΔSOFA score for 28-day mortality. Met...

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Bibliografische Detailangaben
Hauptverfasser: Qian Su, Jie Yu, Shuangjun He, Chenyu Fan, Yi Chen, Wei Zhou, MinJie Qiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-03-01
Schriftenreihe:BMC Emergency Medicine
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Online-Zugang:https://doi.org/10.1186/s12873-026-01547-2
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