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Clonality of HTLV-1–infected T cells as a risk indicator for development and progression of adult T-cell leukemia

Abstract: Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell leukemia virus type 1 (HTLV-1) that develops along a carcinogenic process involving 5 or more genetic events in infected cells. The lifetime incidence of ATL among HTLV-1–infected individuals is approxima...

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Hauptverfasser: Sanaz Firouzi, Amir Farmanbar, Kenta Nakai, Masako Iwanaga, Kaoru Uchimaru, Atae Utsunomiya, Yutaka Suzuki, Toshiki Watanabe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017-06-01
Schriftenreihe:Blood Advances
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2473952920302330
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