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A graded neonatal mouse model of necrotizing enterocolitis demonstrates that mild enterocolitis is sufficient to activate microglia and increase cerebral cytokine expression.

Necrotizing enterocolitis (NEC) is an inflammatory gastrointestinal process that afflicts approximately 10% of preterm infants born in the United States each year, with a mortality rate of 30%. NEC severity is graded using Bell's classification system, from stage I mild NEC to stage III severe NEC....

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Cuilee Sha, Trevor Van Brunt, Jacob Kudria, Donna Schmidt, Alisa Yurovsky, Jela Bandovic, Michael Giarrizzo, Joyce Lin, Styliani-Anna Tsirka, Agnieszka B Bialkowska, Lonnie P Wollmuth, Esther M Speer, Helen Hsieh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2025-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0323626
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