CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections.

Herpesviruses infect the majority of the human population and can cause significant morbidity and mortality. Herpes simplex virus (HSV) type 1 causes cold sores and herpes simplex keratitis, whereas HSV-2 is responsible for genital herpes. Human cytomegalovirus (HCMV) is the most common viral cause...

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Autors principals:	Ferdy R van Diemen, Elisabeth M Kruse, Marjolein J G Hooykaas, Carlijn E Bruggeling, Anita C Schürch, Petra M van Ham, Saskia M Imhof, Monique Nijhuis, Emmanuel J H J Wiertz, Robert Jan Lebbink
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2016-06-01
Col·lecció:	PLoS Pathogens
Accés en línia:	https://doi.org/10.1371/journal.ppat.1005701
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