A Microfluidic In Vitro Three-Dimensional Dynamic Model of the Blood–Brain Barrier to Study the Transmigration of Immune Cells

To study the biodistribution of new chemical and biological entities, an in vitro model of the blood–brain barrier (BBB) may become an essential tool during early phases of drug discovery. Here, we present a proof-of-concept of an in-house designed three-dimensional BBB biochip designed by us. This...

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Auteurs principaux:	Megha Meena, Robin Vandormael, Maxime De Laere, Isabel Pintelon, Zwi Berneman, Regan Watts, Nathalie Cools
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2022-09-01
Collection:	Brain Sciences
Sujets:	blood–brain barrier central nervous system endothelial cells TripleB slides microfluidic device transendothelial electrical resistance
Accès en ligne:	https://www.mdpi.com/2076-3425/12/10/1293
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