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NMDA receptor antagonists as potential therapy in cerebellar degenerative disorders

Cerebellar degeneration remains a poorly studied topic. Excitotoxicity, i.e. neuronal damage and death due to excess activation of postsynaptic N-methyl-D-aspartate receptors (NMDAR) by glutamate, is considered to be a universal mechanism of most neurodegenerative conditions. The use of antagonists...

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Principais autores: Olga S. Belozor, Andrey N. Shuvaev, Yana V. Fritsler, Anton N. Shuvaev
Formato: Artigo
Idioma:Inglês
Publicado: Research Center of Neurology 2022-06-01
Series:Анналы клинической и экспериментальной неврологии
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Acceso en liña:https://annaly-nevrologii.com/journal/pathID/article/viewFile/862/633
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