Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2

Abstract Background The ongoing COVID-19 pandemic has resulted in 185 million recorded cases and over 4 million deaths worldwide. Several COVID-19 vaccines have been approved for emergency use in humans and are being used in many countries. However, all the approved vaccines are administered by intr...

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Hauptverfasser:	Huibi Cao, Juntao Mai, Zhichang Zhou, Zhijie Li, Rongqi Duan, Jacqueline Watt, Ziyan Chen, Ranmal Avinash Bandara, Ming Li, Sang Kyun Ahn, Betty Poon, Natasha Christie-Holmes, Scott D. Gray-Owen, Arinjay Banerjee, Karen Mossman, Rob Kozak, Samira Mubareka, James M. Rini, Jim Hu, Jun Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2021-12-01
Schriftenreihe:	Cell & Bioscience
Schlagworte:	COVID-19 HD-Ad Nasal delivery SARS-CoV2 Vaccine
Online-Zugang:	https://doi.org/10.1186/s13578-021-00723-0
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