ABCG2 polymorphism and rivaroxaban pharmacokinetics in healthy individuals after a single dose

Rivaroxaban is a direct factor Xa inhibitor. Its interindividual variability is large and may be connected to the occurrence of adverse drug reactions or drug inefficacy. Pharmacogenetics studies concentrating on the reasons underlying rivaroxaban's inadequate response could help explain the differe...

Description complète

Détails bibliographiques

Auteurs principaux:	A.F. dos Santos, Q.A.S Francisco, J.B. Nunes, F.A. Colombo, V.B. Boralli
Format:	Artigo
Langue:	Inglês
Publié:	Associação Brasileira de Divulgação Científica 2024-07-01
Collection:	Brazilian Journal of Medical and Biological Research
Sujets:	Polymorphism Transporter gene Breast cancer resistance protein Direct oral anticoagulants Pharmacokinetics Variability
Accès en ligne:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100650&lng=en&tlng=en
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!