VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans.

BACKGROUND: Glaucoma is a leading cause of blindness worldwide. Nonetheless, the mechanism of its pathogenesis has not been well-elucidated, particularly at the molecular level, because of insufficient availability of experimental genetic animal models. METHODOLOGY/PRINCIPAL FINDINGS: Here we demons...

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Principais autores:	Keiko Fujikawa, Takeshi Iwata, Kaoru Inoue, Masakazu Akahori, Hanako Kadotani, Masahiro Fukaya, Masahiko Watanabe, Qing Chang, Edward M Barnett, Wojciech Swat
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2010-01-01
叢編:	PLoS ONE
在線閱讀:	http://europepmc.org/articles/PMC2816215?pdf=render
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