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Structure and catalytic mechanism of human protein tyrosine phosphatome

Together with protein tyrosine kinases (PTKs), protein tyrosinephosphatases (PTPs) serve as hallmarks in cellular signaltransduction by controlling the reversible phosphorylation oftheir substrates. The human genome is estimated to encodemore than 100 PTPs, which can be divided into elevensub-groups...

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Salvato in:
Autore principale: Seung Jun Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Biochemistry and Molecular Biology 2012-12-01
Serie:BMB Reports
Soggetti:
Classical PTP
Crystal structure
Dual specificity PTP
Eyes absent
Protein tyrosine phosphatase (PTP)
Accesso online:http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTE0MTVAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0xMiU1RDEyMTIyNjE2MjBfJTI4NjkzLTY5OSUyOUJNQl8xMi0yNDAucGRm
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