CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a potential biomarker for prognosis in ccRCC

Abstract Notably, clear cell renal cell carcinoma (ccRCC) is characterized by a distinct metabolic tumor phenotype that involves the reprogramming of multiple metabolic pathways. Although there is increasing evidence linking FUCA1 to malignancies, its specific role and downstream signaling pathways...

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Hauptverfasser:	Shuo Zhao, Jiajia Sun, Qinzheng Chang, Shuo Pang, Nianzhao Zhang, Yidong Fan, Jikai Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-09-01
Schriftenreihe:	Cancer Cell International
Schlagworte:	CTCF Autophagy FUCA1 α-L-fucosidase Clear cell renal cell carcinoma
Online-Zugang:	https://doi.org/10.1186/s12935-024-03502-2
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