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Lamin A/C is a risk biomarker in colorectal cancer.

<h4>Background</h4>A-type lamins are type V intermediate filament proteins encoded by the gene LMNA. Mutations in LMNA give rise to diverse degenerative diseases related to premature ageing. A-type lamins also influence the activity of the Retinoblastoma protein (pRb) and oncogenes such a beta-caten...

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Hoofdauteurs: Naomi D Willis, Thomas R Cox, Syed F Rahman-Casañs, Kim Smits, Stefan A Przyborski, Piet van den Brandt, Manon van Engeland, Matty Weijenberg, Robert G Wilson, Adriaan de Bruïne, Christopher J Hutchison
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2008-08-01
Reeks:PLoS ONE
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18714339/?tool=EBI
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