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Dynamics of spike-specific neutralizing antibodies across five-year emerging SARS-CoV-2 variants of concern reveal conserved epitopes that protect against severe COVID-19

IntroductionSince early 2020, several SARS-CoV-2 variants of concern (VOCs) continue to emerge, evading waning antibody mediated immunity produced by the current Spike-alone based COVID-19 vaccines. This caused a prolonged and persistent COVID-19 pandemic that is going to enter its fifth year. Thus,...

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Hoofdauteurs: Latifa Zayou, Swayam Prakash, Hawa Vahed, Nisha Rajeswari Dhanushkodi, Afshana Quadiri, Ahmed Belmouden, Zohra Lemkhente, Aziz Chentoufi, Daniel Gil, Jeffrey B. Ulmer, Lbachir BenMohamed
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2025-02-01
Reeks:Frontiers in Immunology
Onderwerpen:
SARS-CoV-2
COVID-19
B cell epitopes
antibodies
age
gender
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1503954/full
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