TWEAK/Fn14 axis-targeted therapeutics: Moving basicscience discoveries to the clinic
The TNF superfamily member TWEAK (TNFSF12) is a multifunctional cytokine implicated in physiological tissue regeneration and wound repair. TWEAK is initially synthesized as a membrane-anchored protein, but furin cleavage within the stalk region can generate a secreted TWEAK isoform. Both TWEAK isofo...
Kaydedildi:
| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2013-12-01
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| Seri Bilgileri: | Frontiers in Immunology |
| Konular: | |
| Online Erişim: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00473/full |
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