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Activation phenotypes defined by the coordinated expression of activation markers discriminate TCR-mediated and bystander T cell responses

Summary: Studying activation of antigen-specific T cells is essential for understanding adaptive immune response to pathogens, tumors, and vaccines. Flow cytometry is commonly used to identify antigen-specific T cells based on the induction of activation-induced markers (AIMs). However, these marker...

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Principais autores: Tamara J.C. Schenk, Martijn Vos, Yannick van Sleen, Debbie van Baarle, Teun Guichelaar
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2026-02-01
Serija:iScience
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2589004225028123
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